Gene Function: Cell Signaling

Functional and statistical data for significant genes

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GO Legend: Biological Process (P) Molecular Function (F) Cellular Component (C)
Sequence & Stats Description GO Annotations Gene Function
SRR924327_primary_scf7180002275798_257-1470
Len: 1,213 bp
Hits: 20
E-val: 1.20E-193
Sim: 91.45%
 XP_026068438.1gap junction gamma-1 protein-like
GO:0007267P:cell-cell signaling
GO:0055085P:transmembrane transport
GO:0005243F:gap junction channel activity
GO:0005922C:connexin complex
Cell Signaling
SRR924327_primary_scf7180002276031_1-1037
Len: 1,036 bp
Hits: 20
E-val: 1.20E-165
Sim: 95.83%
 XP_016424447.1 bone morphogenetic protein receptor type-2 isoform X1
GO:0001945P:lymph vessel development
GO:0001947P:heart looping
GO:0002040P:sprouting angiogenesis
GO:0003146P:heart jogging
GO:0030509P:BMP signaling pathway
GO:0031101P:fin regeneration
GO:0032924P:activin receptor signaling pathway
GO:0048570P:notochord morphogenesis
GO:2000354P:regulation of ovarian follicle development
GO:0005025F:transforming growth factor beta receptor activity, type I
GO:0005026F:transforming growth factor beta receptor activity, type II
GO:0005524F:ATP binding
GO:0016361F:activin receptor activity, type I
GO:0016362F:activin receptor activity, type II
GO:0070123F:transforming growth factor beta receptor activity, type III
GO:0098821F:BMP receptor activity
GO:0005886C:plasma membrane
GO:0043235C:receptor complex
Cell Signaling
SRR924327_primary_scf7180002276634_1-795
Len: 794 bp
Hits: 20
E-val: 8.00E-114
Sim: 97.53%
 XP_018973828.1 hyaluronan synthase 2
GO:0000271P:polysaccharide biosynthetic process
GO:0001568P:blood vessel development
GO:0001756P:somitogenesis
GO:0001947P:heart looping
GO:0003146P:heart jogging
GO:0003181P:atrioventricular valve morphogenesis
GO:0008078P:mesodermal cell migration
GO:0021535P:cell migration in hindbrain
GO:0030213P:hyaluronan biosynthetic process
GO:0030510P:regulation of BMP signaling pathway
GO:0031101P:fin regeneration
GO:0035810P:positive regulation of urine volume
GO:0036302P:atrioventricular canal development
GO:0060030P:dorsal convergence
GO:0070295P:renal water absorption
GO:0085029P:extracellular matrix assembly
GO:0050501F:hyaluronan synthase activity
GO:0000139C:Golgi membrane
GO:0005764C:lysosome
GO:0005789C:endoplasmic reticulum membrane
GO:0005886C:plasma membrane
GO:0031982C:vesicle
Cell Signaling
SRR924327_primary_scf7180002276793_1-1320
Len: 1,319 bp
Hits: 20
E-val: 9.00E-195
Sim: 87.54%
 XP_026121528.1prickle-like protein 1
GO:0000132P:establishment of mitotic spindle orientation
GO:0001755P:neural crest cell migration
GO:0001764P:neuron migration
GO:0001947P:heart looping
GO:0003407P:neural retina development
GO:0016055P:Wnt signaling pathway
GO:0021535P:cell migration in hindbrain
GO:0031175P:neuron projection development
GO:0035622P:intrahepatic bile duct development
GO:0042074P:cell migration involved in gastrulation
GO:0060027P:convergent extension involved in gastrulation
GO:0070121P:Kupffer's vesicle development
GO:0071907P:determination of digestive tract left/right asymmetry
GO:0071910P:determination of liver left/right asymmetry
GO:0008270F:zinc ion binding
GO:0012505C:endomembrane system
GO:0016020C:membrane
Cell Signaling
SRR924327_primary_scf7180002276886_523-1024
Len: 501 bp
Hits: 20
E-val: 5.00E-21
Sim: 86.07%
 XP_027006884.1LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 2-like
GO:0034220P:monoatomic ion transmembrane transport
GO:0035249P:synaptic transmission, glutamatergic
GO:0050804P:modulation of chemical synaptic transmission
GO:0015277F:kainate selective glutamate receptor activity
GO:1904315F:transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO:0032983C:kainate selective glutamate receptor complex
GO:0042734C:presynaptic membrane
GO:0098839C:postsynaptic density membrane
Cell Signaling
SRR924327_primary_scf7180002277163_340-819
Len: 479 bp
Hits: 20
E-val: 3.80E-79
Sim: 95.84%
 XP_018953047.1 peroxisome proliferator-activated receptor gamma-like
GO:0000122P:negative regulation of transcription by RNA polymerase II
GO:0009755P:hormone-mediated signaling pathway
GO:0010887P:negative regulation of cholesterol storage
GO:0030154P:cell differentiation
GO:0030522P:intracellular receptor signaling pathway
GO:0045923P:positive regulation of fatty acid metabolic process
GO:0045944P:positive regulation of transcription by RNA polymerase II
GO:0048511P:rhythmic process
GO:0050728P:negative regulation of inflammatory response
GO:0000978F:RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227F:DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0004879F:nuclear receptor activity
GO:0008270F:zinc ion binding
GO:0005634C:nucleus
GO:0005737C:cytoplasm
Cell Signaling
SRR924327_primary_scf7180002277311_128-1037
Len: 909 bp
Hits: 20
E-val: 4.90E-99
Sim: 92.18%
 XP_018953971.1 transmembrane protein 2
GO:0001947P:heart looping
GO:0003190P:atrioventricular valve formation
GO:0003197P:endocardial cushion development
GO:0003318P:cell migration to the midline involved in heart development
GO:0016203P:muscle attachment
GO:0030111P:regulation of Wnt signaling pathway
GO:0030214P:hyaluronan catabolic process
GO:0055008P:cardiac muscle tissue morphogenesis
GO:0060974P:cell migration involved in heart formation
GO:1900748P:positive regulation of vascular endothelial growth factor signaling pathway
GO:1901203P:positive regulation of extracellular matrix assembly
GO:1903670P:regulation of sprouting angiogenesis
GO:0004415F:hyalurononglucosaminidase activity
GO:0005509F:calcium ion binding
GO:0030246F:carbohydrate binding
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002277349_1-1123
Len: 1,122 bp
Hits: 20
E-val: 2.00E-17
Sim: 94.47%
 XP_018920183.1 lymphoid enhancer-binding factor 1-like
GO:0006357P:regulation of transcription by RNA polymerase II
GO:0060070P:canonical Wnt signaling pathway
GO:0060429P:epithelium development
GO:0000978F:RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981F:DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000785C:chromatin
GO:1990907C:beta-catenin-TCF complex
Cell Signaling
SRR924327_primary_scf7180002277913_1-1048
Len: 1,047 bp
Hits: 20
E-val: 5.20E-44
Sim: 51.32%
 XP_026125996.1semaphorin-3F-like
GO:0001755P:neural crest cell migration
GO:0007165P:signal transduction
GO:0007411P:axon guidance
GO:0030335P:positive regulation of cell migration
GO:0050919P:negative chemotaxis
GO:0071526P:semaphorin-plexin signaling pathway
GO:0005102F:signaling receptor binding
GO:0030215F:semaphorin receptor binding
GO:0045499F:chemorepellent activity
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002277917_464-991
Len: 527 bp
Hits: 20
E-val: 5.00E-96
Sim: 99.94%
 NP_956287.1ADP-ribosylation factor 6
GO:0006886P:intracellular protein transport
GO:0010976P:positive regulation of neuron projection development
GO:0021510P:spinal cord development
GO:0030838P:positive regulation of actin filament polymerization
GO:0030866P:cortical actin cytoskeleton organization
GO:0032456P:endocytic recycling
GO:0035020P:regulation of Rac protein signal transduction
GO:0035622P:intrahepatic bile duct development
GO:0036010P:protein localization to endosome
GO:0043523P:regulation of neuron apoptotic process
GO:0050714P:positive regulation of protein secretion
GO:0051489P:regulation of filopodium assembly
GO:0051549P:positive regulation of keratinocyte migration
GO:0055113P:epiboly involved in gastrulation with mouth forming second
GO:0060998P:regulation of dendritic spine development
GO:0090162P:establishment of epithelial cell polarity
GO:0097178P:ruffle assembly
GO:0097284P:hepatocyte apoptotic process
GO:0120183P:positive regulation of focal adhesion disassembly
GO:1900141P:regulation of oligodendrocyte apoptotic process
GO:1902217P:erythrocyte apoptotic process
GO:1903078P:positive regulation of protein localization to plasma membrane
GO:1903438P:positive regulation of mitotic cytokinetic process
GO:1905345P:protein localization to cleavage furrow
GO:2000009P:negative regulation of protein localization to cell surface
GO:0003925F:G protein activity
GO:0005525F:GTP binding
GO:0019003F:GDP binding
GO:0031996F:thioesterase binding
GO:0035591F:signaling adaptor activity
GO:0005829C:cytosol
GO:0005938C:cell cortex
GO:0030139C:endocytic vesicle
GO:0031527C:filopodium membrane
GO:0032154C:cleavage furrow
GO:0032587C:ruffle membrane
GO:0055038C:recycling endosome membrane
GO:0090543C:Flemming body
Cell Signaling
SRR924327_primary_scf7180002278003_1-895
Len: 894 bp
Hits: 20
E-val: 9.30E-103
Sim: 92.74%
 CAA74974.1D4A Dopamine receptor
GO:0001963P:synaptic transmission, dopaminergic
GO:0007195P:adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0014059P:regulation of dopamine secretion
GO:0021514P:ventral spinal cord interneuron differentiation
GO:0021520P:spinal cord motor neuron cell fate specification
GO:0043266P:regulation of potassium ion transport
GO:0051481P:negative regulation of cytosolic calcium ion concentration
GO:0051967P:negative regulation of synaptic transmission, glutamatergic
GO:0060158P:phospholipase C-activating dopamine receptor signaling pathway
GO:0071881P:adenylate cyclase-inhibiting adrenergic receptor signaling pathway
GO:0001591F:dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0004938F:alpha2-adrenergic receptor activity
GO:0005886C:plasma membrane
GO:0045202C:synapse
Cell Signaling
SRR924327_primary_scf7180002278105_1-1061
Len: 1,060 bp
Hits: 20
E-val: 1.10E-17
Sim: 95.15%
 CAG14653.1unnamed protein product, partial
GO:0007186P:G protein-coupled receptor signaling pathway
GO:0007214P:gamma-aminobutyric acid signaling pathway
GO:0004965F:G protein-coupled GABA receptor activity
GO:0038039C:G protein-coupled receptor heterodimeric complex
Cell Signaling
SRR924327_primary_scf7180002278387_173-457
Len: 284 bp
Hits: 20
E-val: 5.10E-31
Sim: 74.1%
 XP_009295692.1suppressor of tumorigenicity 14 protein-like
GO:0019221P:cytokine-mediated signaling pathway
GO:0048008P:platelet-derived growth factor receptor signaling pathway
GO:0048010P:vascular endothelial growth factor receptor signaling pathway
GO:0071363P:cellular response to growth factor stimulus
GO:0005003F:ephrin receptor activity
GO:0005017F:platelet-derived growth factor receptor activity
GO:0005488F:binding
GO:0008236F:serine-type peptidase activity
GO:0016020C:membrane
Cell Signaling
SRR924327_primary_scf7180002279252_106-759
Len: 653 bp
Hits: 20
E-val: 5.00E-21
Sim: 99.64%
 AAH90296.1Cltcb protein
GO:0000278P:mitotic cell cycle
GO:0006886P:intracellular protein transport
GO:0006898P:receptor-mediated endocytosis
GO:0048268P:clathrin coat assembly
GO:0005198F:structural molecule activity
GO:0032051F:clathrin light chain binding
GO:0005819C:spindle
GO:0030130C:clathrin coat of trans-Golgi network vesicle
GO:0030132C:clathrin coat of coated pit
GO:0045334C:clathrin-coated endocytic vesicle
GO:0070062C:extracellular exosome
GO:0071439C:clathrin complex
Cell Signaling
SRR924327_primary_scf7180002279688_294-1085
Len: 791 bp
Hits: 20
E-val: 1.80E-137
Sim: 83.47%
 XP_018952504.1 semaphorin-4D-like
GO:0000122P:negative regulation of transcription by RNA polymerase II
GO:0001755P:neural crest cell migration
GO:0007411P:axon guidance
GO:0030335P:positive regulation of cell migration
GO:0043931P:ossification involved in bone maturation
GO:0050919P:negative chemotaxis
GO:0071526P:semaphorin-plexin signaling pathway
GO:0030215F:semaphorin receptor binding
GO:0045499F:chemorepellent activity
GO:0005615C:extracellular space
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002279752_658-921
Len: 263 bp
Hits: 20
E-val: 3.80E-36
Sim: 93.69%
 XP_018938525.1 reelin-like
GO:0001764P:neuron migration
GO:0006508P:proteolysis
GO:0007155P:cell adhesion
GO:0007417P:central nervous system development
GO:0015074P:DNA integration
GO:0003676F:nucleic acid binding
GO:0008236F:serine-type peptidase activity
GO:0046872F:metal ion binding
GO:0070325F:lipoprotein particle receptor binding
GO:0005615C:extracellular space
GO:0043005C:neuron projection
Cell Signaling
SRR924327_primary_scf7180002280517_1-666
Len: 665 bp
Hits: 20
E-val: 3.20E-47
Sim: 75.11%
 XP_016085598.1 cadherin-23-like
GO:0006897P:endocytosis
GO:0016477P:cell migration
GO:0035678P:neuromast hair cell morphogenesis
GO:0050910P:detection of mechanical stimulus involved in sensory perception of sound
GO:0050957P:equilibrioception
GO:0060117P:auditory receptor cell development
GO:0060122P:inner ear receptor cell stereocilium organization
GO:0061512P:protein localization to cilium
GO:0098609P:cell-cell adhesion
GO:0008013F:beta-catenin binding
GO:0022857F:transmembrane transporter activity
GO:0045296F:cadherin binding
GO:0005929C:cilium
GO:0016342C:catenin complex
Cell Signaling
SRR924327_primary_scf7180002280962_1-515
Len: 514 bp
Hits: 20
E-val: 1.90E-68
Sim: 91.23%
 XP_018944787.1 nuclear receptor subfamily 2 group F member 1-B-like
GO:0000122P:negative regulation of transcription by RNA polymerase II
GO:0030154P:cell differentiation
GO:0030522P:intracellular receptor signaling pathway
GO:0035284P:brain segmentation
GO:0035476P:angioblast cell migration
GO:0060841P:venous blood vessel development
GO:1904888P:cranial skeletal system development
GO:0000978F:RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0004879F:nuclear receptor activity
GO:0008270F:zinc ion binding
GO:0005634C:nucleus
Cell Signaling
SRR924327_primary_scf7180002281118_1-969
Len: 968 bp
Hits: 20
E-val: 3.00E-30
Sim: 95.62%
 XP_018957997.1 E3 ubiquitin-protein ligase TRIM37
GO:0006513P:protein monoubiquitination
GO:0051865P:protein autoubiquitination
GO:0070842P:aggresome assembly
GO:0005164F:tumor necrosis factor receptor binding
GO:0008270F:zinc ion binding
GO:0016874F:ligase activity
GO:0031625F:ubiquitin protein ligase binding
GO:0061630F:ubiquitin protein ligase activity
GO:0005778C:peroxisomal membrane
GO:0016235C:aggresome
GO:0035098C:ESC/E(Z) complex
Cell Signaling
SRR924327_primary_scf7180002281266_1-1179
Len: 1,178 bp
Hits: 20
E-val: 5.10E-24
Sim: 99.84%
 XP_018918955.1 netrin receptor UNC5D-like
GO:0007411P:axon guidance
GO:0038007P:netrin-activated signaling pathway
GO:0005042F:netrin receptor activity
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002281884_94-1026
Len: 932 bp
Hits: 20
E-val: 2.80E-174
Sim: 85.17%
 XP_018927604.1 adenosine receptor A2b-like
GO:0001973P:G protein-coupled adenosine receptor signaling pathway
GO:0007189P:adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0001609F:G protein-coupled adenosine receptor activity
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002282288_1-650
Len: 649 bp
Hits: 20
E-val: 1.50E-94
Sim: 83.78%
 XP_016390060.1 glutamate receptor ionotropic, NMDA 2B-like
GO:0034220P:monoatomic ion transmembrane transport
GO:0035235P:ionotropic glutamate receptor signaling pathway
GO:0004972F:NMDA glutamate receptor activity
GO:0045211C:postsynaptic membrane
Cell Signaling
SRR924327_primary_scf7180002282860_348-1193
Len: 845 bp
Hits: 20
E-val: 2.50E-142
Sim: 91.63%
 XP_018937809.1 beta-2 adrenergic receptor-like
GO:0043410P:positive regulation of MAPK cascade
GO:0071880P:adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0004930F:G protein-coupled receptor activity
GO:0005886C:plasma membrane
Cell Signaling
SRR924327_primary_scf7180002284105_1-793
Len: 792 bp
Hits: 20
E-val: 1.10E-17
Sim: 90.07%
 XP_026097000.1importin subunit beta-1-like
GO:0006606P:protein import into nucleus
GO:0048513P:animal organ development
GO:0008139F:nuclear localization sequence binding
GO:0031267F:small GTPase binding
GO:0061608F:nuclear import signal receptor activity
GO:0005635C:nuclear envelope
GO:0005737C:cytoplasm
GO:0016020C:membrane
Cell Signaling
SRR924327_primary_scf7180002284117_1-317
Len: 316 bp
Hits: 20
E-val: 7.50E-23
Sim: 99.9%
 XP_016105374.1 A disintegrin and metalloproteinase with thrombospondin motifs 20-like
GO:0006508P:proteolysis
GO:0007229P:integrin-mediated signaling pathway
GO:0030198P:extracellular matrix organization
GO:0004222F:metalloendopeptidase activity
GO:0008270F:zinc ion binding
GO:0005576C:extracellular region
GO:0031012C:extracellular matrix
Cell Signaling