Gene Function: Cell Signaling

Functional and statistical data for significant genes

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GO Legend: Biological Process (P) Molecular Function (F) Cellular Component (C)
Sequence & Stats Description GO Annotations Gene Function
SRR941867_primary_scf7180002378195_1-1058
Len: 1,057 bp
Hits: 20
E-val: 1.70E-10
Sim: 99.87%
 XP_026097000.1importin subunit beta-1-like
GO:0006606P:protein import into nucleus
GO:0048513P:animal organ development
GO:0008139F:nuclear localization sequence binding
GO:0031267F:small GTPase binding
GO:0061608F:nuclear import signal receptor activity
GO:0005635C:nuclear envelope
GO:0005737C:cytoplasm
GO:0016020C:membrane
Cell Signaling
SRR941867_primary_scf7180002378583_439-840
Len: 401 bp
Hits: 20
E-val: 1.40E-29
Sim: 69.18%
 XP_026126264.1semaphorin-3B-like isoform X1
GO:0001755P:neural crest cell migration
GO:0007411P:axon guidance
GO:0030335P:positive regulation of cell migration
GO:0050919P:negative chemotaxis
GO:0071526P:semaphorin-plexin signaling pathway
GO:0030215F:semaphorin receptor binding
GO:0038191F:neuropilin binding
GO:0045499F:chemorepellent activity
GO:0005886C:plasma membrane
Cell Signaling
SRR941867_primary_scf7180002378871_81-1820
Len: 1,739 bp
Hits: 20
E-val: 1.60E-21
Sim: 99.9%
 XP_026126386.11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2-like isoform X3
GO:0006508P:proteolysis
GO:0016042P:lipid catabolic process
GO:0046488P:phosphatidylinositol metabolic process
GO:0048015P:phosphatidylinositol-mediated signaling
GO:0051209P:release of sequestered calcium ion into cytosol
GO:0004177F:aminopeptidase activity
GO:0004435F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005509F:calcium ion binding
GO:0008236F:serine-type peptidase activity
GO:0015276F:ligand-gated monoatomic ion channel activity
GO:0016020C:membrane
Cell Signaling
SRR941867_primary_scf7180002379472_1-839
Len: 838 bp
Hits: 20
E-val: 1.90E-57
Sim: 65.17%
 XP_016089253.1 mothers against decapentaplegic homolog 1
GO:0009880P:embryonic pattern specification
GO:0009953P:dorsal/ventral pattern formation
GO:0030509P:BMP signaling pathway
GO:0045892P:negative regulation of DNA-templated transcription
GO:0061515P:myeloid cell development
GO:0000976F:transcription cis-regulatory region binding
GO:0003700F:DNA-binding transcription factor activity
GO:0005515F:protein binding
GO:0005634C:nucleus
GO:0005667C:transcription regulator complex
Cell Signaling
SRR941867_primary_scf7180002379690_119-1046
Len: 927 bp
Hits: 20
E-val: 2.00E-68
Sim: 99.02%
 XP_026135333.1glutamate receptor 3-like isoform X2
GO:0034220P:monoatomic ion transmembrane transport
GO:0015276F:ligand-gated monoatomic ion channel activity
GO:0038023F:signaling receptor activity
GO:0045211C:postsynaptic membrane
Cell Signaling
SRR941867_primary_scf7180002379908_1-403
Len: 402 bp
Hits: 20
E-val: 3.50E-25
Sim: 90.04%
 XP_026124897.1vacuolar fusion protein MON1 homolog B-like isoform X1
GO:0006623P:protein targeting to vacuole
GO:0099152P:regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane
GO:0099158P:regulation of recycling endosome localization within postsynapse
GO:1905244P:regulation of modification of synaptic structure
GO:0035658C:Mon1-Ccz1 complex
GO:0098837C:postsynaptic recycling endosome
GO:0098978C:glutamatergic synapse
GO:0098998C:extrinsic component of postsynaptic early endosome membrane
Cell Signaling
SRR941867_primary_scf7180002380732_1-640
Len: 639 bp
Hits: 20
E-val: 2.00E-51
Sim: 95.52%
 RXN03629.1junction plakoglobin-like protein
GO:0002160P:desmosome maintenance
GO:0003181P:atrioventricular valve morphogenesis
GO:0030178P:negative regulation of Wnt signaling pathway
GO:0034334P:adherens junction maintenance
GO:0045944P:positive regulation of transcription by RNA polymerase II
GO:0060070P:canonical Wnt signaling pathway
GO:0070121P:Kupffer's vesicle development
GO:0098609P:cell-cell adhesion
GO:0003713F:transcription coactivator activity
GO:0016922F:nuclear receptor binding
GO:0019903F:protein phosphatase binding
GO:0045294F:alpha-catenin binding
GO:0045296F:cadherin binding
GO:0005634C:nucleus
GO:0005737C:cytoplasm
GO:0005856C:cytoskeleton
GO:0005912C:adherens junction
GO:0014704C:intercalated disc
GO:0016342C:catenin complex
GO:0030057C:desmosome
Cell Signaling
SRR941867_primary_scf7180002381323_1-978
Len: 977 bp
Hits: 20
E-val: 1.80E-136
Sim: 88.98%
 XP_026115488.1tensin-2-like isoform X2
GO:0046627P:negative regulation of insulin receptor signaling pathway
GO:0004725F:protein tyrosine phosphatase activity
GO:0046872F:metal ion binding
GO:0005925C:focal adhesion
Cell Signaling
SRR941867_primary_scf7180002381700_1-980
Len: 979 bp
Hits: 20
E-val: 1.40E-27
Sim: 90.35%
 XP_018947316.1 low-density lipoprotein receptor-related protein 2-like
GO:0003094P:glomerular filtration
GO:0007507P:heart development
GO:0048259P:regulation of receptor-mediated endocytosis
GO:0070293P:renal absorption
GO:0005041F:low-density lipoprotein particle receptor activity
GO:0005509F:calcium ion binding
GO:0042562F:hormone binding
GO:0016324C:apical plasma membrane
GO:0043235C:receptor complex
Cell Signaling
SRR941867_primary_scf7180002381947_1-1009
Len: 1,008 bp
Hits: 20
E-val: 1.90E-83
Sim: 86.47%
 XP_018935077.1 sesquipedalian-1-like
GO:0001881P:receptor recycling
GO:0007032P:endosome organization
GO:0042147P:retrograde transport, endosome to Golgi
GO:0060271P:cilium assembly
GO:1904888P:cranial skeletal system development
GO:0005769C:early endosome
GO:0005802C:trans-Golgi network
GO:0005829C:cytosol
GO:0030136C:clathrin-coated vesicle
GO:0055037C:recycling endosome
Cell Signaling
SRR941867_primary_scf7180002382115_297-1469
Len: 1,172 bp
Hits: 20
E-val: 2.80E-67
Sim: 66.83%
 XP_016334227.1 low-density lipoprotein receptor-related protein 2-like, partial
GO:0003094P:glomerular filtration
GO:0007507P:heart development
GO:0048259P:regulation of receptor-mediated endocytosis
GO:0070293P:renal absorption
GO:0005488F:binding
GO:0005886C:plasma membrane
Cell Signaling
SRR941867_primary_scf7180002383138_826-1244
Len: 418 bp
Hits: 20
E-val: 1.40E-40
Sim: 97.78%
 XP_018922669.1 vang-like protein 2
GO:0000132P:establishment of mitotic spindle orientation
GO:0001736P:establishment of planar polarity
GO:0001839P:neural plate morphogenesis
GO:0001841P:neural tube formation
GO:0007015P:actin filament organization
GO:0014812P:muscle cell migration
GO:0021535P:cell migration in hindbrain
GO:0030198P:extracellular matrix organization
GO:0033564P:anterior/posterior axon guidance
GO:0035844P:cloaca development
GO:0035845P:photoreceptor cell outer segment organization
GO:0036342P:post-anal tail morphogenesis
GO:0045813P:positive regulation of Wnt signaling pathway, calcium modulating pathway
GO:0048048P:embryonic eye morphogenesis
GO:0048570P:notochord morphogenesis
GO:0048840P:otolith development
GO:0048884P:neuromast development
GO:0055002P:striated muscle cell development
GO:0060028P:convergent extension involved in axis elongation
GO:0060030P:dorsal convergence
GO:0060071P:Wnt signaling pathway, planar cell polarity pathway
GO:0060271P:cilium assembly
GO:0060971P:embryonic heart tube left/right pattern formation
GO:0071679P:commissural neuron axon guidance
GO:0090090P:negative regulation of canonical Wnt signaling pathway
GO:0097475P:motor neuron migration
GO:0005515F:protein binding
GO:0005886C:plasma membrane
Cell Signaling
SRR941867_primary_scf7180002384532_1030-1353
Len: 323 bp
Hits: 20
E-val: 5.50E-21
Sim: 98.99%
 XP_016375546.1 phosphatidylinositide phosphatase SAC1-A-like
GO:0032480P:negative regulation of type I interferon production
GO:0039536P:negative regulation of RIG-I signaling pathway
GO:0045893P:positive regulation of DNA-templated transcription
GO:0046856P:phosphatidylinositol dephosphorylation
GO:0003676F:nucleic acid binding
GO:0004438F:phosphatidylinositol-3-phosphate phosphatase activity
GO:0043812F:phosphatidylinositol-4-phosphate phosphatase activity
GO:0000139C:Golgi membrane
GO:0005789C:endoplasmic reticulum membrane
GO:0140268C:endoplasmic reticulum-plasma membrane contact site
Cell Signaling
SRR941867_primary_scf7180002385073_254-1123
Len: 869 bp
Hits: 20
E-val: 2.20E-16
Sim: 100%
 CAD61074.1novel protein similar to human signal transducer and activator of transcription 4 (STAT4), partial
GO:0001570P:vasculogenesis
GO:0006357P:regulation of transcription by RNA polymerase II
GO:0006952P:defense response
GO:0007259P:cell surface receptor signaling pathway via JAK-STAT
GO:0019221P:cytokine-mediated signaling pathway
GO:0042127P:regulation of cell population proliferation
GO:0043434P:response to peptide hormone
GO:0060429P:epithelium development
GO:0000978F:RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981F:DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005737C:cytoplasm
GO:0090575C:RNA polymerase II transcription regulator complex
Cell Signaling
SRR941867_primary_scf7180002385716_1-817
Len: 816 bp
Hits: 20
E-val: 1.10E-17
Sim: 97.92%
 XP_016389080.1 LOW QUALITY PROTEIN: cadherin-23
GO:0006897P:endocytosis
GO:0007156P:homophilic cell-cell adhesion
GO:0016477P:cell migration
GO:0035678P:neuromast hair cell morphogenesis
GO:0050910P:detection of mechanical stimulus involved in sensory perception of sound
GO:0050957P:equilibrioception
GO:0055085P:transmembrane transport
GO:0060117P:auditory receptor cell development
GO:0060122P:inner ear receptor cell stereocilium organization
GO:0061512P:protein localization to cilium
GO:0005509F:calcium ion binding
GO:0008013F:beta-catenin binding
GO:0022857F:transmembrane transporter activity
GO:0045296F:cadherin binding
GO:0005911C:cell-cell junction
GO:0005929C:cilium
GO:0016342C:catenin complex
Cell Signaling
SRR941867_primary_scf7180002386101_1-1658
Len: 1,657 bp
Hits: 20
E-val: 3.80E-25
Sim: 97.55%
 XP_016346070.1 transmembrane protein 132E isoform X1
GO:0035677P:posterior lateral line neuromast hair cell development
GO:0050910P:detection of mechanical stimulus involved in sensory perception of sound
GO:0060117P:auditory receptor cell development
GO:0016020C:membrane
Cell Signaling
SRR941867_primary_scf7180002387489_1-711
Len: 710 bp
Hits: 20
E-val: 8.10E-17
Sim: 97.92%
 XP_026108032.1glutamate receptor 1-like
GO:0034220P:monoatomic ion transmembrane transport
GO:0035235P:ionotropic glutamate receptor signaling pathway
GO:0035249P:synaptic transmission, glutamatergic
GO:0050804P:modulation of chemical synaptic transmission
GO:0060078P:regulation of postsynaptic membrane potential
GO:0004971F:AMPA glutamate receptor activity
GO:1904315F:transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO:0032281C:AMPA glutamate receptor complex
GO:0043197C:dendritic spine
GO:0098839C:postsynaptic density membrane
Cell Signaling
SRR941867_primary_scf7180002388938_1-728
Len: 727 bp
Hits: 20
E-val: 1.20E-20
Sim: 98.35%
 XP_016386989.1 transcription elongation factor SPT5-like
GO:0001764P:neuron migration
GO:0006414P:translational elongation
GO:0021954P:central nervous system neuron development
GO:0032968P:positive regulation of transcription elongation by RNA polymerase II
GO:0034244P:negative regulation of transcription elongation by RNA polymerase II
GO:0040037P:negative regulation of fibroblast growth factor receptor signaling pathway
GO:0046427P:positive regulation of receptor signaling pathway via JAK-STAT
GO:0060335P:positive regulation of type II interferon-mediated signaling pathway
GO:0140673P:transcription elongation-coupled chromatin remodeling
GO:1902038P:positive regulation of hematopoietic stem cell differentiation
GO:0003677F:DNA binding
GO:0003729F:mRNA binding
GO:0003746F:translation elongation factor activity
GO:0032044C:DSIF complex
Cell Signaling
SRR941867_primary_scf7180002389733_1-600
Len: 599 bp
Hits: 20
E-val: 3.20E-67
Sim: 73.64%
 XP_018969394.1 LOW QUALITY PROTEIN: cation-independent mannose-6-phosphate receptor-like
GO:0007041P:lysosomal transport
GO:0005520F:insulin-like growth factor binding
GO:0005537F:D-mannose binding
GO:0038023F:signaling receptor activity
GO:0000139C:Golgi membrane
GO:0005770C:late endosome
GO:0005802C:trans-Golgi network
GO:0005886C:plasma membrane
GO:0010008C:endosome membrane
Cell Signaling
SRR941867_primary_scf7180002390090_243-1173
Len: 930 bp
Hits: 20
E-val: 1.90E-50
Sim: 96.82%
 RXN33048.1D(2)-like dopamine receptor
GO:0001963P:synaptic transmission, dopaminergic
GO:0007195P:adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0014059P:regulation of dopamine secretion
GO:0043266P:regulation of potassium ion transport
GO:0051481P:negative regulation of cytosolic calcium ion concentration
GO:0051967P:negative regulation of synaptic transmission, glutamatergic
GO:0060158P:phospholipase C-activating dopamine receptor signaling pathway
GO:0071881P:adenylate cyclase-inhibiting adrenergic receptor signaling pathway
GO:0001591F:dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO:0004938F:alpha2-adrenergic receptor activity
GO:0042734C:presynaptic membrane
GO:0098978C:glutamatergic synapse
Cell Signaling
SRR941867_primary_scf7180002391046_1-1221
Len: 1,220 bp
Hits: 20
E-val: 3.30E-50
Sim: 98.05%
 XP_026107858.1voltage-dependent calcium channel gamma-3 subunit-like
GO:0019226P:transmission of nerve impulse
GO:0051968P:positive regulation of synaptic transmission, glutamatergic
GO:0070588P:calcium ion transmembrane transport
GO:0098943P:neurotransmitter receptor transport, postsynaptic endosome to lysosome
GO:0098970P:postsynaptic neurotransmitter receptor diffusion trapping
GO:0099590P:neurotransmitter receptor internalization
GO:0005245F:voltage-gated calcium channel activity
GO:0016247F:channel regulator activity
GO:0032281C:AMPA glutamate receptor complex
GO:0098839C:postsynaptic density membrane
Cell Signaling
SRR941867_primary_scf7180002392527_1-1141
Len: 1,140 bp
Hits: 20
E-val: 2.00E-57
Sim: 92.79%
 XP_018979832.1 FERM domain-containing protein 6-like isoform X1
GO:0035332P:positive regulation of hippo signaling
GO:0005856C:cytoskeleton
GO:0098592C:cytoplasmic side of apical plasma membrane
Cell Signaling
SRR941867_primary_scf7180002392836_1-971
Len: 970 bp
Hits: 20
E-val: 8.80E-30
Sim: 99.1%
 XP_018975463.1 LOW QUALITY PROTEIN: phosphatase and actin regulator 4B-like
GO:0001755P:neural crest cell migration
GO:0001843P:neural tube closure
GO:0007266P:Rho protein signal transduction
GO:0030036P:actin cytoskeleton organization
GO:0048484P:enteric nervous system development
GO:0051726P:regulation of cell cycle
GO:0061386P:closure of optic fissure
GO:2001045P:negative regulation of integrin-mediated signaling pathway
GO:0003779F:actin binding
GO:0008157F:protein phosphatase 1 binding
GO:0072542F:protein phosphatase activator activity
GO:0005737C:cytoplasm
GO:0030027C:lamellipodium
Cell Signaling
SRR941867_primary_scf7180002394021_1-898
Len: 897 bp
Hits: 20
E-val: 8.70E-32
Sim: 91.06%
 XP_018952995.1 aryl hydrocarbon receptor-like
GO:0006357P:regulation of transcription by RNA polymerase II
GO:0006805P:xenobiotic metabolic process
GO:0030522P:intracellular receptor signaling pathway
GO:0000976F:transcription cis-regulatory region binding
GO:0004879F:nuclear receptor activity
GO:0046983F:protein dimerization activity
GO:0005634C:nucleus
GO:0005667C:transcription regulator complex
GO:0005737C:cytoplasm
GO:0034751C:aryl hydrocarbon receptor complex
Cell Signaling
SRR941867_primary_scf7180002395756_367-1444
Len: 1,077 bp
Hits: 20
E-val: 4.70E-32
Sim: 100%
 ROI48919.1Sn1-specific diacylglycerol lipase alpha
GO:0007409P:axonogenesis
GO:0007634P:optokinetic behavior
GO:0019369P:arachidonate metabolic process
GO:0036269P:swimming behavior
GO:0046340P:diacylglycerol catabolic process
GO:0071926P:endocannabinoid signaling pathway
GO:0098921P:retrograde trans-synaptic signaling by endocannabinoid
GO:0004465F:lipoprotein lipase activity
GO:0005737C:cytoplasm
GO:0032590C:dendrite membrane
GO:0045211C:postsynaptic membrane
Cell Signaling